Dutch Lipid Clinic Network Score (DLCNS) for Familial Hypercholesterolemia (FH)
Dutch Lipid Clinic Network Score (DLCNS) for Familial Hypercholesterolemia (FH) Part 1 - Family History Group 1 - Each is worth 1 point, maximum possible 1 point [select name="Q1" value="YES=0.5|no=0"] <-- First degree relative with known premature coronary and/or vascular disease (men aged <55 years, women aged <60 years) [select name="Q2" value="YES=0.5|no=0"] <-- First degree relative with known LDL-cholesterol above the 95th percentile for age and gender Group 2 - Each is worth 2 points, maximum possible 2 points [select name="Q3" value="YES=0.5|no=0"] <-- First degree relative with tendinous xanthomata and/or arcus cornealis [select name="Q4" value="YES=0.5|no=0"] <-- Children aged <18 years with LDL-cholesterol above the 95th percentile for age and gender Part 2 - Clinical History [select name="Q5" value="YES=2|no=0"] <-- Patients with premature coronary artery disease (men aged <55 years, women aged <60 years) (0 to 2 points) [select name="Q6" value="YES=1|no=0"] <-- Patients with premature cerebral or peripheral vascular disease (men aged <55 years, women aged <60 years) (0 to 1 point) Part 3 - Physical Examination [select name="Q7" value="YES=6|no=0"] <-- Tendinous xanthomata (0 to 6 points) [select name="Q8" value="YES=4|no=0"] <-- Arcus cornealis before 45 years of age (0 to 4 points) [select name="Q9" value="Greater than 8.5 mmol per L or 330 mg per dL=8|6.5 to 8.4 mmol per L or 250 to 329 mg per dL=5|5.0 to 6.4 mmol per L or 190 to 249 mg per dL=3|4.0 to 4.9 mmol per L or 155 to 189 mg per dL=1|Less than 4.0 mmol per L or 155 mg per dL=0"] <-- Untreated LDL Cholesterol (0 to 8 points) Score --> [calc memo="number" value="score=(Math.round((Q1)+(Q2)))+(2*(Math.round((Q3)+(Q4))))+(Q5)+(Q6)+(Q7)+(Q8)+(Q9)"] Interpretation --> [calc memo="result" value="score2=(Math.round((Q1)+(Q2)))+(2*(Math.round((Q3)+(Q4))))+(Q5)+(Q6)+(Q7)+(Q8)+(Q9);score2>8?'Diagnosis of Familial Hypercholesterolemia is CERTAIN':score2>5?'Diagnosis of Familial Hypercholesterolemia is PROBABLE':score2>2?'Diagnosis of Familial Hypercholesterolemia is POSSIBLE':'Diagnosis of Familial Hypercholesterolemia is UNLIKELY'"] [checkbox memo="References (Hide/Show)" name="footnotes" value=""][conditional field="footnotes" condition="(footnotes).isNot('')"][link url="http://apps.who.int/iris/bitstream/10665/66346/1/WHO_HGN_FH_CONS_99.2.pdf" memo="World Health Organization. Familial hypercholesterolemia—report of a second WHO Consultation. Geneva, Switzerland: World Health Organization; 1999"][/conditional]
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